Mixing Xanax And Cocaine

Mixing Xanax and Cocaine on table

Taking cocaine and Xanax together is common due to the fact that the two drugs have counteracting effects. Cocaine, also known as coke, blow or snow, is a stimulant that at first makes people feel extremely happy, energetic and alert. However, once the effects wear off, people tend to feel very depressed, anxious or angry. Some people find that mixing cocaine and Xanax while coming down from a cocaine high helps reduce these negative feelings and help them sleep easier. Xanax is a benzodiazepine often prescribed for anxiety and panic disorders. It can produce unpleasant side effects such as tiredness and problems focusing. Some people combine Xanax and coke to make them more alert while on the benzodiazepine.

Should You Mix Xanax and Cocaine?

It is bad to mix Xanax and coke. Taking either drug alone is potentially dangerous, both because they each have many harmful side effects and because each of these substances is very addictive. Mixing the two drugs together can increase their side effects and increase a person’s chances of overdose.

Combining them can also make it more likely for a person to become physically dependent on or addicted to either drug. It’s also harder to recover from an addiction when someone has been using more than one substance. While many people think they can mix Xanax and coke, it will often lead to serious problems.

Side Effects of Mixing Xanax and Cocaine

What happens when you mix Xanax and coke? One of the main problems is that each of the drugs has negative side effects that worsen once they’re mixed with other substances.

Some of the side effects of taking Xanax are:

  • Tiredness
  • Dizziness
  • Irritability and restlessness
  • Sweating
  • Blurry vision
  • Depression

People who have taken cocaine may experience:

  • Euphoria
  • Irritability and anger
  • Paranoia
  • Feeling more sensitive to sights, sounds, and touch
  • Rapid or irregular heartbeat
  • Breathing problems

The interaction between cocaine and Xanax can also lead to mental health effects. People taking Xanax, cocaine or both may be more likely to engage in risky behavior. Additionally, when the effects of cocaine start to wear off and a person begins to “crash,” they often feel more depressed. Because Xanax is a “downer” or depressant, it also increases feelings of sadness, hopelessness, and depression. People combining these substances may be more at risk of suicide. Additionally, if someone has a pre-existing mental health disorder, taking multiple substances can make symptoms of that disorder worse.

Risks of Mixing Xanax and Cocaine

Because stimulants and depressants have opposing effects, taking cocaine and Xanax together can sometimes mask their overall effects. For example, Xanax slows down different vital functions in the body, but cocaine speeds them up. Someone who has taken too much Xanax might start to have their heart rate or breathing rate slow down, but they may not notice right away because the cocaine is making them feel more energetic.

Over time, repeated use of these drugs can lead to more serious health effects. If both substances are used regularly at high doses, a person’s liver may have a hard time processing them quickly enough, which can lead to toxins building up in a person’s body. Long-term cocaine and Xanax interaction can lead to organ damage, heart problems, and sexual problems.


Cross-tolerance of drugs occurs when becoming dependent on one drug makes a person more likely to become dependent on a second drug. Usually, this happens between drugs that are in the same category or work the same way. While Xanax and cocaine have opposite effects on the body, both increase dopamine signaling in the brain.

It’s possible that people may experience cross-tolerance between Xanax and cocaine if they regularly use both. When people develop drug dependence, they will start to experience withdrawal symptoms and cravings once the drug starts to leave their system.

Can You Overdose on Xanax and Cocaine?

The chance of someone having a Xanax and coke overdose increases when the two drugs are taken together. People who combine these two substances should be aware of the overdose symptoms for each.

Symptoms of a Xanax overdose include:

  • Decreased heart rate
  • Low body temperature, which might look like cold or bluish skin
  • Confusion
  • Breathing difficulties
  • Muscle weakness or lack of muscle control
  • Exhaustion
  • Passing out

When someone overdoses on cocaine, they might experience:

  • Increased heart rate
  • High body temperature
  • Sweating
  • Shaking
  • Nausea
  • Losing touch with reality
  • Stroke
  • Heart attack
  • Respiratory failure

If someone thinks they are experiencing an overdose from either Xanax or cocaine, they should seek medical attention immediately. Overdoses from both of these compounds can be serious or even deadly. Medical professionals can provide life support or give people medications to counteract uncomfortable or dangerous symptoms.

Getting Help for Xanax and Cocaine Addiction

Over half of admissions to substance abuse treatment programs consist of people who are misusing more than one drug. This is known as polysubstance abuse. When people are dealing with abusing multiple substances, treatment may be more difficult.

For example, withdrawing from a drug after someone is dependent on it can be dangerous and difficult. Withdrawal from Xanax alone can lead to seizures. Cocaine withdrawal can lead to extreme depression. Medical detox is often recommended for both of these drugs. Substance abuse experts can help people stay safe and avoid temptation while they are going through withdrawal. In some cases, doctors may prescribe medication to help ease the detox process. When someone is detoxing from two drugs at once, a different approach to medical detox may be necessary.

In 2018, nearly 4% of adults had both a substance use disorder and a mental illness. When someone with a substance abuse problem also has a mental health disorder, it is called a co-occurring disorder. People who have a mental health disorder and who are looking for Xanax and cocaine addiction treatment should seek out a facility that is trained in dual diagnosis so that underlying mental health problems can be addressed while the person is going through rehab.

People who need cocaine or Xanax treatment in the Pacific Northwest can contact The Recovery Village Ridgefield. Our team can help you identify which programs might help you or a loved one who is dealing with Xanax or cocaine abuse. Our inpatient and outpatient rehab programs can address polysubstance abuse and co-occurring mental health disorder. Call us today to learn how you can get the help you deserve.

National Institute on Drug Abuse. “What are the short-term effects of cocaine use?” Cocaine: Research Report Series, Updated May 2016. Accessed September 27, 2019.

National Institute on Drug Abuse. “What classes of prescription drugs are commonly misused?” Misuse of Prescription Drugs, December 2018. Accessed September 27, 2019.

Substance Abuse and Mental Health Services Administration. “Key Substance Use and Mental Health Indicators in the United States: Results from the 2018 National Survey on Drug Use and Health.” 2019. Accessed September 27, 2019.

Substance Abuse and Mental Health Services Administration. “Treatment Episode Data Set (TEDS): 2002-2012. National Admissions to Substance Abuse Treatment Services.” 2014. Accessed September 27, 2019.

Medical Disclaimer: The Recovery Village aims to improve the quality of life for people struggling with a substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare provider.