Dilaudid Overdose – Deaths & Statistics
Written by The Recovery Village Ridgefield
& Medically Reviewed by Dr. Kevin Wandler, MD
Medically Reviewed
Up to Date
What Is Hydromorphone (Dilaudid)?
Hydromorphone, known by its brand name Dilaudid, is a prescription opioid medication used to manage moderate to severe pain. It belongs to the same family of drugs as morphine, oxycodone and heroin. Hydromorphone is typically prescribed for people who experience severe pain, such as after surgery or during treatment for cancer or other chronic conditions. This potent opioid works by binding to specific receptors in the central nervous system (primarily mu-opioid receptors) and blocking pain signals, thus providing significant pain relief.
When used correctly under the supervision of a medical professional, hydromorphone can improve quality of life for individuals struggling with debilitating pain. However, as with most opioids, hydromorphone also carries a high risk of misuse, dependence and addiction. Because hydromorphone is stronger than many other opioid medications, it can quickly lead to tolerance, meaning a person requires higher or more frequent doses to achieve the same level of pain relief or euphoria. This trajectory can significantly increase the chances of harmful effects, including overdose.
Dilaudid comes in several forms, including oral tablets, liquid solutions and injectable formulations. The injectable form is often administered in clinical settings for acute pain management, while tablets and solutions may be prescribed for home use. Regardless of form, the potency of hydromorphone means it must be used carefully to avoid dangerous side effects and potential overdose.
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Effects of Hydromorphone
When taken as prescribed, hydromorphone can be an effective way to manage pain and improve daily functioning. However, the drug also produces other effects due to its impact on the central nervous system. Common effects include:
- Pain Relief: Hydromorphone reduces the perception of pain by altering the way the brain processes pain signals. This can provide significant relief for individuals with moderate to severe pain.
- Euphoria: Like other opioids, hydromorphone can produce a feeling of well-being or intense pleasure, particularly at higher doses. This euphoric effect plays a significant role in the drug’s potential for misuse.
- Sedation: Hydromorphone often causes drowsiness. Some people may feel profoundly sleepy or struggle to stay alert while on the medication.
- Reduced Anxiety: Opioids can temporarily reduce anxiety or feelings of stress, which can become another factor that perpetuates misuse.
- Respiratory Depression: High doses of hydromorphone can dangerously slow down breathing, a potentially life-threatening effect that underscores the risk of overdose.
- Constipation: Opioids commonly slow digestion, leading to constipation. Over time, this side effect can become chronic and uncomfortable.
- Nausea and Vomiting: Some people experience gastrointestinal symptoms, including nausea, vomiting and stomach upset.
- Dizziness and Confusion: Opioids can impair cognition and cause dizziness or mental fog, increasing the risk of accidents.
The presence and intensity of these effects can vary depending on factors like dosage, body chemistry and presence of other substances. Anyone taking hydromorphone should follow their doctor’s instructions and report any problematic side effects immediately.
Hydromorphone Misuse
Hydromorphone misuse occurs when someone uses the drug in a way that is not prescribed. This can include:
- Taking higher or more frequent doses than prescribed
- Using someone else’s prescription
- Using the drug to experience euphoria rather than pain relief
- Taking hydromorphone in a manner other than intended, such as crushing pills for snorting or injecting
Misuse can lead to dependence, in which a person’s body and brain adapt to the presence of the opioid. Once physical dependence develops, suddenly stopping or reducing use can lead to withdrawal symptoms, including restlessness, muscle pain, insomnia, diarrhea and vomiting.
Psychological dependence can also occur. Someone who misuses hydromorphone may become preoccupied with obtaining or using the drug, neglecting daily responsibilities or relationships. This behavior can escalate to opioid use disorder, a chronic condition characterized by compulsive drug-seeking despite harmful consequences.
A major driver behind the misuse of hydromorphone is its potent painkilling and euphoric effects. However, these same properties that make it highly effective at controlling severe pain also make it a prime target for misuse. Recognizing the signs of misuse early is crucial in preventing progression to addiction and potential overdose.
Signs of Hydromorphone Addiction
Addiction to hydromorphone (often clinically referred to as opioid use disorder) may develop gradually. Common signs can include:
- Increased Tolerance: Needing higher doses of hydromorphone to achieve the same effect is often the first red flag.
- Cravings: Experiencing powerful urges or cravings to use hydromorphone, even when not in pain.
- Neglecting Responsibilities: Missing work, school or family events due to hydromorphone use or recovery from its effects.
- Social Withdrawal: Losing interest in hobbies, friends or activities once enjoyed.
- Continuing Use Despite Harm: Persisting in hydromorphone use even when it causes financial, legal or relationship problems.
- Doctor Shopping: Visiting multiple doctors or pharmacies to obtain more prescriptions than would normally be allowed.
- Using Larger Quantities: Consuming more of the drug than intended, or for a longer period than originally planned.
- Withdrawal Symptoms: Experiencing unpleasant physical symptoms (like vomiting, anxiety, agitation or flu-like discomfort) when trying to cut back or quit.
Opioid addiction can be debilitating and isolating, but with proper treatment and support, people can and do recover. Recognizing these warning signs early gives individuals the best chance of seeking professional help before more severe consequences, like overdose, occur.
Mixing Hydromorphone with Other Substances
Combining hydromorphone with other substances significantly increases the risk of dangerous side effects, including respiratory depression, coma and even death. Some common substance combinations to be aware of include:
- Alcohol: Mixing any opioid with alcohol amplifies sedation and respiratory depression, raising the likelihood of overdose. Both substances depress the central nervous system, leading to slowed breathing, decreased heart rate and a higher risk of organ failure.
- Benzodiazepines: Drugs like alprazolam (Xanax), diazepam (Valium) or clonazepam (Klonopin) are sometimes prescribed for anxiety, insomnia or other conditions. However, using them alongside hydromorphone intensifies the sedative effects and can dangerously lower a person’s breathing rate.
- Other Opioids: Combining hydromorphone with other opioid medications like oxycodone or morphine can dramatically increase the risk of overdose, as the opioids’ effects stack, overwhelming the body’s ability to maintain normal respiratory function.
- Illicit Substances: When hydromorphone is used in conjunction with illicit drugs, such as heroin or fentanyl, the chances of overdose skyrocket. These substances may be contaminated or far stronger than anticipated, posing grave dangers to someone who has already increased their risk profile by using opioids.
Given these risks, it is vital for anyone prescribed hydromorphone to disclose all medications, supplements and substances they use to their healthcare provider. This transparency can help prevent dangerous drug interactions and ensure that the benefits of pain relief are not overshadowed by risks to health and safety.
Hydromorphone Overdose
An overdose occurs when a toxic amount of a substance overwhelms the body’s ability to cope. For hydromorphone, an overdose most often results from taking too much at once or mixing hydromorphone with other sedating substances (especially alcohol or benzodiazepines). Because hydromorphone depresses respiratory function, the most life-threatening aspect of an overdose is respiratory failure. Signs of a hydromorphone overdose include:
- Extremely Slow or Shallow Breathing: The most immediate danger, as insufficient oxygen can lead to organ damage, coma or death.
- Unresponsiveness: The person may be difficult or impossible to wake.
- Pinpoint Pupils: Opioid overdoses often present with constricted pupils.
- Bluish Skin or Lips: Known as cyanosis, this is a sign of oxygen deprivation.
- Weak Pulse or Low Blood Pressure: Overdose can lead to dangerously low cardiovascular function.
- Gurgling or Choking Sounds: This may indicate that the airway is partially obstructed.
If you suspect someone is experiencing a hydromorphone overdose, call emergency services immediately. Administering naloxone (Narcan) can be life-saving in cases of opioid overdose. Naloxone is an opioid antagonist that binds to the same receptors in the brain as hydromorphone but does not activate them. By displacing the opioid, naloxone can quickly reverse respiratory depression, restoring normal breathing. However, naloxone is not a substitute for medical care; professional evaluation and treatment are still necessary once a person has stabilized.
Treatment for Hydromorphone Addiction
Treating hydromorphone addiction often involves a comprehensive approach that addresses both the physical and psychological aspects of opioid dependence. Multiple evidence-based strategies are available:
Medical Detox
Detox is the process of ridding the body of hydromorphone and managing withdrawal symptoms. In a medical setting, health professionals can closely monitor vital signs and offer medications like buprenorphine or methadone to reduce withdrawal’s severity. Medical detox helps keep patients safe and more comfortable, increasing the likelihood of completing the withdrawal phase successfully.
Inpatient Rehab
Inpatient or residential programs provide 24-hour support in a structured environment. Patients receive a combination of medical supervision, counseling, therapy and life-skills training. This setting removes individuals from daily triggers or temptations, allowing them to focus entirely on recovery.
Partial Hospitalization Programs (PHP) & Intensive Outpatient Programs (IOP)
After completing residential treatment or if a person’s addiction is less severe, PHPs and IOPs offer intensive therapy and support while allowing participants to return home in the evenings. This format can provide a strong bridge between around-the-clock care and independent living.
Therapy and Counseling
Behavioral therapies, such as cognitive-behavioral therapy (CBT) and dialectical behavior therapy (DBT), help individuals identify and change destructive thought patterns. Therapy can also address co-occurring mental health disorders, such as depression or anxiety, that may contribute to substance use. Group therapy and family therapy offer peer support and improve relationship dynamics, which can be crucial for sustained recovery.
Medication-Assisted Treatment (MAT)
MAT involves combining medications like methadone, buprenorphine or naltrexone with counseling and other recovery-focused therapies. These medications help stabilize brain chemistry, reduce cravings and lower the risk of relapse. Although some people remain on these medications long-term, others taper off once they have developed sufficient coping strategies.
Aftercare and Support Groups
Recovery is an ongoing journey. Support groups like Narcotics Anonymous (NA) or SMART Recovery provide peer support, accountability and practical guidance for maintaining a drug-free lifestyle. Many treatment centers also offer alumni programs or ongoing counseling sessions that help people stay connected to their recovery community.
Seeking help for hydromorphone addiction is a brave step. With the right treatment plan and ongoing support, most people can overcome opioid dependence and lead healthier, more fulfilling lives.
Dilaudid Overdose Prevention
If you have been prescribed Dilaudid, it is crucial that you take it only as prescribed and avoid mixing it with alcohol or other drugs unless instructed otherwise by your doctor. You should also store your Dilaudid safely away from children and refrain from giving your Dilaudid to others.
If you are abusing prescription drugs, do so close to help in case of an overdose and ask your doctor for a naloxone prescription.
Contact The Recovery Village Ridgefield today to speak with a representative about how professional addiction treatment can address your substance use disorder. You deserve a healthier future, call today.
Sources
Lowe, A; Hamilton, M; Greenall, J; Ma, J; Dhalla, I; Persaud, N. “Fatal overdoses involving hydromorphone and morphine among inpatients: a case series.” CMAJ Open, March 2, 2017. Accessed July 25, 2019.
RxList. “Dilaudid.” Updated October 9, 2018. Accessed July 25, 2019.
CNN Health. “Opioid Crisis Fast Facts.” July 18, 2019. Accessed July 25, 2019.
National Institute on Drug Abuse. “Opioid Overdose Crisis.” January, 2019. Accessed July 25, 2019.
Tinker, Ben; Howard, Jacqueline; Gumbrecht, Jaime. “US Drug Overdose Deaths Fell Slightly in 2018.” CNN, July 17, 2019. Accessed July 25, 2019.
National Institute on Drug Abuse. “Opioid Overdose Reversal With Naloxone.” April, 2018. Accessed July 25, 2019.
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